Araştırma Makalesi
Yıl 2020,
Cilt: 6 Sayı: 2, 92 - 98, 04.03.2020
Öz
Kaynakça
- 1. Kucukler FK, Simsek Y, Baglicaklioglu M, Adali G, Guler S. Acute pancreatitis and type 2 diabetes mellitus: who is guilty? Eur Res J 2015;1:74-7.
- 2. Papachristou GI, Muddana V, Yadav D, O'Connell M, Sanders MK, Slivka A, et al. Comparison of BISAP, Ranson's, APACHE-II, and CTSI scores in predicting organ failure, complications, and mortality in acute pancreatitis. Am J Gastroenterol 2010;105:435-41.
- 3. Wang X, Cui Z, Zhang J, Li H, Zhang D, Miao B, et al. Early predictive factors of in-hospital mortality in patients with severe acute pancreatitis. Pancreas 2010;39:114-5.
- 4. Cho JH, Kim TN, Chung HH, Kim KH. Comparison of scoring systems in predicting the severity of acute pancreatitis. World J Gastroenterol 2015;21:2387-94.
- 5. Fisic E, Poropat G, Bilic-Zulle L, Licul V, Milic S, Stimac D, et al. The role of IL-6, 8, and 10, sTNFr, CRP, and pancreatic elastase in the prediction of systemic complications in patients with acute pancreatitis. Gastroenterol Res Pract 2013;2013:2826-45.
- 6. Patel KV, Semba RD, Ferrucci L, Newman AB, Fried LP, Wallace RB, et al. Red cell distribution width and mortality in older adults: a meta-analysis. J Gerontol A Biol Sci Med Sci 2009;65:258-65.
- 7. Budak YU, Huysal K, Gecgel SK, Ari H, Melek M, Yavuz S, et al. Red cell distribution width, other hematological parameters and atherogenic index of plasma in patients with clopidogrel and aspirin resistance. Eur Res J 2016;2:200-5.
- 8. Agarwal S. Red cell distribution width, inflammatory markers and cardiorespiratory fitness: results from the National Health and Nutrition Examination Survey. Indian Heart J 2012;64:380-7.
- 9. Seretis C, Seretis F, Lagoudianakis E, Gemenetzis G, Salemis NS. Is red cell distribution width a novel biomarker of breast cancer activity? Data from a pilot study. J Clin Med Res 2013;5:121-6.
- 10. Şenol K, Saylam B, Kocaay F, Tez M. Red cell distribution width as a predictor of mortality in acute pancreatitis. Am J Emerg Med 2013;31:687-9.
- 11. Wang D, Yang J, Zhang J, Li H, Zhang D, Miao B, et al. Red cell distribution width predicts deaths in patients with acute pancreatitis. J Res Med Sci 2015;20:42-4.
- 12. Banks P, Bollen T, Dervenis C, Gooszen HG, Johnson CD, Sarr MG, et al. Classification of acute pancreatitis-2012: revision of the Atlanta classification and definitions by international concensus. Gut 2013;62:102-11.
- 13. Makhoul BF, Khourieh A, Kaplan M, Bahouth F, Aronson D, Azzam ZS, et al. Relation between changes in red cell distribution width and clinical outcomes in acute decompensated heart failure. Int J Cardiol 2013;167:1412-6.
- 14. Hong N, Oh J, Kang S-M, Kim SY, Won H, Youn JC, et al. Red blood cell distribution width predicts early mortality in patients with acute dyspnea. Clin Chim Acta 2012;413:992-7.
- 15. Braun E, Domany E, Kenig Y, Mazor Y, Makhoul BF, Azzam ZS, et al. Elevated red cell distribution width predicts poor outcome in young patients with community acquired pneumonia. Crit Care 2011;15:R194.
- 16. Li Y, Zhao Y, Feng L, Guo R. Comparison of the prognostic values of inflammation markers in patients with acute pancreatitis: a retrospective cohort study. BMJ Open 2017;7:13206.
- 17. Çetinkaya E, Şenol K, Saylam B, Tez M. Red cell distribution width to platelet ratio: new and promising prognostic marker in acute pancreatitis. World J Gastroenterol 2014;20:14450-54.
- 18. Song CS, Park DI, Yoon MY, Seok HS, Park JH, Kim HJ, et al. Association between red cell distribution width and disease activity in patients with inflammatory bowel disease. Dig Dis Sci 2012;57:1033-8.
- 19. Ku NS, Kim H-w, Oh HJ, Kim YC, Kim MH, Song JE, et al. Red blood cell distribution width is an independent predictor of mortality in patients with gram-negative bacteremia. Shock 2012;38:123-7.
Red cell distribution width and red cell distribution width to total serum calcium ratio as predictors of mortality in acute pancreatitis: a retrospective cohort study
Öz
Objectives:
We
investigated whether red cell
distribution width (RDW) and red cell distribution width to total serum calcium
(RDW-to-TSC) ratio were associated with mortality in patients with acute
pancreatitis (AP).
Methods: A
total of 170 patients who present emergency department between January 2017 and June 2018 with a
diagnosis of AP were enrolled in this study. A comparison between survivor and nonsurvivor AP patients
was performed. Diagnosis of AP were defined according to the revised Atlanta
classification 2012. Variables evaluated included demographics, hospital
stay, laboratorial parameters and mortality.
Results: AP
related in-hospital mortality was 6.4%. Red cell distribution (RDW), white
blood cell (WBC), platelet, serum
glucose and RDW-to-TSC ratio were associated with AP mortality. RDW-to-TSC ratio had the
highest AUC (0.88; 95% CI, 0.756-1.0), followed by RDW, serum glucose, platelet and WBC (AUC = 0.801, 0.797, 0.743 and
0.687 respectively). A cut-off value of RDW-to-TSC
ratio >2.0, the highest sensitivity (91.9%), specificity (81.1%), PPV
(82.9%), and NPV (91.1%) were achieved for prediction of AP related in-hospital
mortality in approximately 86.5% of the cases (p < 0.001).
Conclusions: RDW
and TSC are simple, inexpensive routine
serum parameters, provided in a complete blood count test and available at
admission. This study
showed that RDW > 16.6 and RDW-to-TSC > 2.0 were very good predictors for
AP mortality.
Anahtar Kelimeler
acute pancreatitis mortality red cell distribution width serum calcium
Kaynakça
- 1. Kucukler FK, Simsek Y, Baglicaklioglu M, Adali G, Guler S. Acute pancreatitis and type 2 diabetes mellitus: who is guilty? Eur Res J 2015;1:74-7.
- 2. Papachristou GI, Muddana V, Yadav D, O'Connell M, Sanders MK, Slivka A, et al. Comparison of BISAP, Ranson's, APACHE-II, and CTSI scores in predicting organ failure, complications, and mortality in acute pancreatitis. Am J Gastroenterol 2010;105:435-41.
- 3. Wang X, Cui Z, Zhang J, Li H, Zhang D, Miao B, et al. Early predictive factors of in-hospital mortality in patients with severe acute pancreatitis. Pancreas 2010;39:114-5.
- 4. Cho JH, Kim TN, Chung HH, Kim KH. Comparison of scoring systems in predicting the severity of acute pancreatitis. World J Gastroenterol 2015;21:2387-94.
- 5. Fisic E, Poropat G, Bilic-Zulle L, Licul V, Milic S, Stimac D, et al. The role of IL-6, 8, and 10, sTNFr, CRP, and pancreatic elastase in the prediction of systemic complications in patients with acute pancreatitis. Gastroenterol Res Pract 2013;2013:2826-45.
- 6. Patel KV, Semba RD, Ferrucci L, Newman AB, Fried LP, Wallace RB, et al. Red cell distribution width and mortality in older adults: a meta-analysis. J Gerontol A Biol Sci Med Sci 2009;65:258-65.
- 7. Budak YU, Huysal K, Gecgel SK, Ari H, Melek M, Yavuz S, et al. Red cell distribution width, other hematological parameters and atherogenic index of plasma in patients with clopidogrel and aspirin resistance. Eur Res J 2016;2:200-5.
- 8. Agarwal S. Red cell distribution width, inflammatory markers and cardiorespiratory fitness: results from the National Health and Nutrition Examination Survey. Indian Heart J 2012;64:380-7.
- 9. Seretis C, Seretis F, Lagoudianakis E, Gemenetzis G, Salemis NS. Is red cell distribution width a novel biomarker of breast cancer activity? Data from a pilot study. J Clin Med Res 2013;5:121-6.
- 10. Şenol K, Saylam B, Kocaay F, Tez M. Red cell distribution width as a predictor of mortality in acute pancreatitis. Am J Emerg Med 2013;31:687-9.
- 11. Wang D, Yang J, Zhang J, Li H, Zhang D, Miao B, et al. Red cell distribution width predicts deaths in patients with acute pancreatitis. J Res Med Sci 2015;20:42-4.
- 12. Banks P, Bollen T, Dervenis C, Gooszen HG, Johnson CD, Sarr MG, et al. Classification of acute pancreatitis-2012: revision of the Atlanta classification and definitions by international concensus. Gut 2013;62:102-11.
- 13. Makhoul BF, Khourieh A, Kaplan M, Bahouth F, Aronson D, Azzam ZS, et al. Relation between changes in red cell distribution width and clinical outcomes in acute decompensated heart failure. Int J Cardiol 2013;167:1412-6.
- 14. Hong N, Oh J, Kang S-M, Kim SY, Won H, Youn JC, et al. Red blood cell distribution width predicts early mortality in patients with acute dyspnea. Clin Chim Acta 2012;413:992-7.
- 15. Braun E, Domany E, Kenig Y, Mazor Y, Makhoul BF, Azzam ZS, et al. Elevated red cell distribution width predicts poor outcome in young patients with community acquired pneumonia. Crit Care 2011;15:R194.
- 16. Li Y, Zhao Y, Feng L, Guo R. Comparison of the prognostic values of inflammation markers in patients with acute pancreatitis: a retrospective cohort study. BMJ Open 2017;7:13206.
- 17. Çetinkaya E, Şenol K, Saylam B, Tez M. Red cell distribution width to platelet ratio: new and promising prognostic marker in acute pancreatitis. World J Gastroenterol 2014;20:14450-54.
- 18. Song CS, Park DI, Yoon MY, Seok HS, Park JH, Kim HJ, et al. Association between red cell distribution width and disease activity in patients with inflammatory bowel disease. Dig Dis Sci 2012;57:1033-8.
- 19. Ku NS, Kim H-w, Oh HJ, Kim YC, Kim MH, Song JE, et al. Red blood cell distribution width is an independent predictor of mortality in patients with gram-negative bacteremia. Shock 2012;38:123-7.
Toplam 19 adet kaynakça vardır.
Ayrıntılar
| Birincil Dil | İngilizce |
|---|---|
| Konular | Acil Tıp |
| Bölüm | Original Article |
| Yazarlar | |
| Yayımlanma Tarihi | 4 Mart 2020 |
| Gönderilme Tarihi | 30 Eylül 2018 |
| Kabul Tarihi | 30 Nisan 2019 |
| Yayımlandığı Sayı | Yıl 2020 Cilt: 6 Sayı: 2 |
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